Specialist Surgeon

Mediclinic Milnerton

General surgical practice based in Cape Town, South Africa.

Dr. Maré Du Plessis offers a range of surgical procedures, with a specialist focus on gastrointestinal surgery, hernia surgery, breast cancer surgery and other breast conditions, as well as thyroid and endocrine conditions.

The practice has an endoscopy suite in-rooms, making a colonoscopy or gastroscopy procedure a comfortable doctor’s visit, rather than necessitating a hospital stay.

Dr Maré Du Plessis is well known for his caring approach to patient care, and his exceptional skill as a surgeon.

He is passionate about making sure his patients receive the best medical services available.

Our Areas of Specialisation

General Surgical Conditions

Dr. Du Plessis performs surgery to treat a range of conditions related to the digestive system, from the oesophagus to the anus. We partner with specialist physicians in gastroenterology, endocrinology and oncology related to breast cancer to provide expert surgical treatment of conditions in these fields.

Surgical Procedures

Dr. Du Plessis has expertise in most abdominal surgical procedures including laparoscopy, gastroscopy, colonoscopy and endoscopy, as well as emergency procedures such as appendectomy and intestinal obstructions. We also handle minor procedures such as removal of cysts and ingrown toenails.

Testimonials

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“I was “assigned” (for lack of a better word) to Dr du Plessis when I was admitted to Milnerton Mediclinic with an emergency over the festive season. He happened to be the surgeon on call that evening, which turned out to be very lucky for me. Not only is he excellent at what he does, but he also has a wonderful bedside manner.

Dr du Plessis took the time to answer all my questions, explained clearly what was happening, and put my mind at ease — while, of course, getting me firmly on the road to recovery. I felt completely safe in his care, confident in his knowledge, skill, and expertise.

He is also backed by a truly phenomenal team. As part of my outpatient follow-up, I needed to visit his rooms and undergo a further procedure. I was looked after by Joelene, Tanya, and Sr Corne. They are warm, friendly, efficient, and absolute pros in their respective fields — genuine gems, every one of them. They have a rare ability to make you feel like you’re their only patient, whether you’re calling about appointment scheduling, the procedure itself, or navigating medical aid queries (what a nightmare!). I never once had to wonder what my next steps were, and I was treated with kindness, care, and a very gentle touch throughout.

I’m almost back to full power, and that’s thanks to Dr du Plessis and his outstanding team (and some pretty good meds 😂).”

- Shani Pretorius

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“Dr Maré du Plessis is an amazing Specialist Surgeon and I can most definitely recommend him for gastroscopies and colonoscopies.

I was extremely anxious about the procedure (and let's not forget the "White Coat Syndrome"), but Dr du Plessis is extremely knowledgeable, kind, patient, understanding and compassionate. He constantly asks if you have questions and takes his time to answer and explain - no rushing.

The rest of the team, Joelene (the receptionist) was always professional, helpful and friendly. Sister Corné was there every step of the way with her calming, bubbly personality...definitely a calling!

Tanya the accountant was just a call away to assist with Medical Aid claims. What a positive experience! Thank you Dr Maré du Plessis and team!”

- Frieda Angerer

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“Such a phenomenal doctor and surgeon. He removed my gallbladder in an emergency situation.

Prior to the surgery he explained the procedure to me and I felt incredibly confident in his ability. Post surgery he saw me on the ward to check I was OK. He also did ward rounds until my discharge. Upon discharge I was given ample medication and understood what each medication was for.

My final consolidation was excellent and I cannot recommend this doctor highly enough. Thank you for the excellent treatment of a 74 year old.”

- Barbara Fuller-gee

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“My mother received exceptional care from Dr. M. Du Plessis. From the very beginning, he took the time to explain everything thoroughly, ensuring that we understood the diagnosis, treatment options, and next steps. His professionalism, patience, and compassionate approach gave me great confidence and peace of mind. He made me feel assured that my mother was in capable hands and would be well taken care of throughout her treatment. I am truly grateful for the excellent care and attention he provided. Highly recommended.”

- Nkcuba

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“Some Heroes don't wear capes, they wear surgical masks - Dr Mare Du Plessis is without a doubt my hero. Some 5+ years ago he did corrective surgery on me for an incisional hernia and he literally saved my life....I had to have surgery almost every year prior to me meeting him...he fixed whatever the other Doctors could not fix and gave me back my life! I will forever be thankful to this brilliant, kind and gentle surgeon - Dr. Maré Du Plessis! I
Highly Recommend him and Trust him with my Life!”

- Thomas Bloem

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“I must say, I’ve previously only gone to gastroenterologists for colonoscopies, and I didn’t realise you could see a surgeon for this procedure. Dr. Duplessis was absolutely fantastic.

From start to finish, the experience was professional, efficient, and incredibly well handled. The nurses were attentive and on the ball, and everyone was so kind and friendly, which really put me at ease. The anaesthetist was lovely too, which made the whole process feel calm and reassuring.

I would highly recommend Dr. Duplessis to anyone needing a colonoscopy.”

- Susy De Mendonca

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“There are no words that could truly express our gratitude for everything you did for Greg after his accident last year. During one of the most frightening and uncertain times of our lives, your skill, dedication, and compassion gave us hope when we needed it most.

Because of you, Greg was given a second chance. The road to recovery was long and challenging, but thanks to your incredible care and the work you did to save his life, he has come so far.
I wanted to share something special with you. Greg has started riding his motorbike again. Watching him do something he loves so much is incredibly emotional for our family. It’s a reminder of how precious life is and how different our story could have been if it weren’t for you and your team.

You didn’t just save Greg’s life—you gave him the opportunity to make more memories with his family, to continue doing what brings him joy, and to be here with us. That is a gift we will never take for granted.
Please know that we think of you often and will always be grateful for your expertise, kindness, and commitment. Thank you for everything you have done for our family. You will always hold a very special place in our hearts.”

- Bernadene Waddington and the Waddington family

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“It was such a pleasure to visit Dr Maré du Plessis and his personnel … from the receptionist, sister, and anaesthetist … all excellent … so friendly and helpful … Dr du Plessis is very lucky to have such good personnel … well done all … 10/10.”

- Thea Groenewald

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“From the first moment my family and I met Dr du Plessis, my heart and mind were at ease. Thank you for your true patience and kindness answering all my lists of questions. Thank you for treating me with true kindness. The process since my first consultation until the operation was explained so clearly. The operation was a huge success. The best surgeon ever, meticulous in his job as a surgeon and I would highly recommend Dr Maré du Plessis, the most kind doctor. I will forever be grateful to our Father God and to you Dr du Plessis.”

- Elza Kallis

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"Dr du Plessis, simply said—BRILLIANT and honest with his feedback and advice … would recommend him to anyone."

- Colleen De Beer

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"My surgeon who dealt with my cancer journey. Couldn’t have been in better hands! Incredibly compassionate and experienced."

- Pauline McMaster De Klerk

“From the receptionist Joelene, to Tanya in accounts and the nurse who takes you through the procedure—you will be going through, Dr du Plessis' staff are amazing. From the first time I called to make an appointment, I was treated with love. That’s the only way I can put it. This practice is unique. Joelene always remembers my voice and has so much patience and an amazingly friendly personality who puts you at ease (especially when I’m calling to move dates around and get more info). They give you all the information you need—Tanya in Accounts broke down the expenses for me so that I had more than an idea of what to expect.

Dr du Plessis himself is so passionate about his patients. Even as a new patient, I felt it. He takes his time, does not rush through anything. And you’re guaranteed to not have any questions because he explains everything in detail. He is very kind and compassionate. Super friendly. I will come back and rate him on his bedside manner after my procedure, but based on his consultation manner, I’d give him full 5 stars. Attentive, observant, reassuring, exhibits full knowledge of his profession, and even extra with knowledge that gets deep into other specialties and how gut health impacts them. He’s very cautious in terms of making sure you prep carefully before a procedure.

I have forgotten the nurse but she is bubbly, very informative, great bedside manner. When you interact with them, you don’t feel like a patient with a file number. They genuinely care about the health of their patients—and will go the extra mile for you. ”

- Mazile Bee

“Dr. du Plessis first operated on me in January, 2021 with an emergency blocked small colon. He was very attentive and excellent. This was during Covid. I was required to stay longer due to minor complications and, at that time, a hernia was detected. It was too risky to operate on that, at that time, and he advised me to have it done in the future.

On 7th October, 2024 I was operated on to repair a very big hernia. After my discharge I developed septicemia and again operated on to remove the mesh. However, on my discharge I experienced terrible pain and had to be operated on again, for the third time, to secure my intestines.
Doctor was in constant touch with my sons to advise them of my condition & progress during all the months of my recovery.
He sought advice, when required, from a physician who continued to work with him on me.

Dr. Mare du Plessis has been the most wonderful, caring and excellent surgeon. He was with me all the way with his expertise, kindness & care to restore me to good health.

I recommend him very highly and thank him for everything.”

- Debbie Epstein

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“My 18-year old daughter, Shanice had an op with Dr. Du Plessis to remove a fibroadenoma in her breast. He handled Shanice with so much care and made her feel very comfortable … I would recommend Dr. Du Plessis as a surgeon to any patient.  His advice and his medical knowledge is the best.”

- Rene Cole

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“I would like to thank you and your team for all the amazing service I received during my hospital stay for surgery for a bilateral inguinal hernia. From the moment I met you my mind was set at ease. The professional yet friendly way things were explained to me was refreshing.”

- Tristan Lee

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"The very thought of hospitalisation is scary and traumatising, but caring doctors like you make it friendly and pleasing.

Your team took care of me as i was the most important person on earth :)"

- Nicole Andrews

Specialist Surgeon
Dr. Maré Du Plessis, MBCHB (UP) MMED Surg (US) FCS (SA)

Mediclinic Milnerton
Suite 169, 1st Floor, Mediclinic Milnerton, Racecourse Road, Milnerton, 7441
P.O Box 61, Plumstead, 7801
Tel: 021 555 1877
Email: milnerton@drduplessis.com
Office Hours:
Mondays - Thursdays: 08h00 – 16h00
Fridays: 08h00 - 13h00
Consultations:
Mondays, Tuesdays and Wednesdays
Surgical Procedures & Endoscopies:
Mondays and Wednesdays
Emergencies: 021 529 9000
Prac.Nr. 0612103